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Excipients Details

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Excipients: Essential Ingredients for Pharmaceutical Formulations

Excipients are non-active ingredients used in pharmaceutical products to enhance the stability, delivery, and effectiveness of active pharmaceutical ingredients (APIs). While excipients do not provide therapeutic effects, they are crucial for the formulation, manufacturing, and delivery of medications.

Key Roles of Excipients:

  • Binders: Hold ingredients together in tablets or capsules.
  • Fillers: Add bulk to formulations, especially when active ingredients are minimal.
  • Disintegrants:Aid in breaking down tablets for better absorption.
  • Lubricants: Prevent sticking during manufacturing.
  • Stabilizers: Maintain the product's integrity and extend shelf life.
  • Preservatives:Protect against microbial growth.
  • Sweeteners & Flavorings:Improve taste, particularly in oral medications.
  • Humectants:Retain moisture to prevent drying.
  • Surfactants:Enhance solubility and bioavailability of APIs.
Excipients CAS Number Segment Grade
Aerosil 112945-52-5 Anti-caking agent USP/BP/IP
Alginic Acid 9005-38-3 Gelling Agent, Stabilizer IP
Bronopal 111-80-8 Emulsifier BP
CMC Sodium (PDV/HVP/DVP) 9004-32-4 Binder, Thickener IP
Crosscarmellose Sodium 74811-65-7 Disintegrant USP
Crospovidone XL-10 9003-39-8 Disintegrant USP/BP/EP
Citric Acid Mono/Anhydrous 77-92-9 Acidulant, Buffer IP
DCP Dihydrate/Anhydrous 10034-99-8 Acidulant, Calcium Salt IP
EDTA Disodium 6381-92-6 Chelating Agent IP
Glycerine 56-81-5 Humectant, Solvent USP/IP
Lactose 63-42-3 Sugar, Carrier IP/BP
Magnesium Stearate 557-04-0 Lubricant IP
Menthol 89-78-1 Flavoring Agent -
Mannitol 69-65-8 Sweetener, Filler IP/BP/USP
MCCP Plain/101/102/112 9004-34-6 Binder, Filler IP
Propyl Gallate 121-79-9 Antioxidant IP
Propylene Glycol 57-55-6 Solvent, Humectant IP
PVP K-30/90 9003-39-8 Binder, Film-forming Agent IP
Methyl Paraben (Plain/Sodium) 99-76-3 Preservative IP
Propyl Paraben (Plain/Sodium) 94-13-3 Preservative IP
Purified Talc (93%/98%) 9005-25-8 Stabilizer, Binder IP
Saccharin Sodium 81-07-2 Sweetener IP/BP
Sodium Alginate 9005-38-3 Gelling Agent IP
Sodium Benzoate 532-32-1 Preservative IP
Sodium Starch Glycolate 9063-38-1 Disintegrant IP
Sorbitol 50-70-4 Humectant, Sweetener IP
Tri Basic Calcium Phosphate 7758-87-4 Calcium Supplement -
Tween 80 9005-65-6 Surfactant, Emulsifier USP/BP
Xanthum Gum 11138-66-2 Stabilizer, Thickener USP/BP/IP
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